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Antibody design · Sequence prediction · Protein Design

IgDesign

Design antibody CDRs against a target antigen by inverse folding.

Runs IgDesign, which conditions on an antigen-antibody complex structure plus the antibody framework sequence and samples new sequences for the CDRs it is given explicit position ranges for. IgDesign's own configuration format takes those ranges directly rather than a numbering scheme, so this does too.

Input

Configure a small job

POST
The framework and antigen are read from this structure; the designed loops are resampled.
One per line, as region:chain:start-end using 1-indexed positions within that chain, for example hcdr3:heavy:96-108. Designed in the order listed. IgDesign's own example configs are the reference for picking these ranges.
Ready
Response

JSON result

{
  "status": "Ready for a request"
}