Structure prediction · Antibody design

ImmuneBuilder

Predict an antibody, nanobody, or TCR structure in seconds.

Runs ABodyBuilder2, NanoBodyBuilder2, or TCRBuilder2 on the supplied variable-domain sequences. These are single-sequence models with no MSA or template search, so a structure comes back in seconds rather than the minutes a general folding model needs.

Home page ↗ Source code ↗

Input

Configure a small job

POST

Job name

Heavy-chain sequence Variable domain only; constant domains are not modelled.

Light-chain sequence

VHH sequence

TCR alpha-chain sequence

TCR beta-chain sequence

Numbering scheme How the residues of the returned structure are numbered.

CPU threads for refinement 0 refines on the GPU; any other value forces OpenMM onto that many CPU threads.

Skip the strained-bond check Slightly faster, at the risk of an occasional unphysical side chain.

Use the original TCRBuilder2 weights Off by default, which uses the newer TCRBuilder2+ weights.

Ready

Response

JSON result

{
  "status": "Ready for a request"
}