ProteinMPNN-ddG

Predict the stability effects of every point mutation in a protein chain.

Runs ProteinMPNN-ddG with full sequence context and writes its saturation-mutagenesis scores as CSV.

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Input

Configure a small job

POST

Protein PDB

Context chains Comma-separated chains; the first is predicted by default.

Chain to predict Optional; defaults to the first context chain.

Model

Random seed

Model repeats

Disable the published ddG correction Required when selecting a model other than v_48_020.

Top mutations to highlight (optional) Return only the K most stability-improving mutations, ranked by predicted ddG. 0 returns the full table only.

Ready

Response

{
  "status": "Ready for a request"
}